Endocrine Abstracts

Background: Hyperosmolar hyperglycaemic state (HHS) is a life-threatening condition that can be the initial presentation of type 2 diabetes mellitus. This condition is characterized by severe hyperglycaemia, a high serum osmolality and dehydration without accumulation of ketoacids. We report two patients who presented with mixed features of HHS and DKA.Case 1: An 11-year-old Afro-Caribbean boy with severe developmental delay presented with a 4-week histo...

Introduction: Cerebral oedema has rarely been reported in adrenal insufficiency. We report a case of decompensated cerebral oedema due to autoimmune adrenalitis.Case report: A 12-year-old boy presented to hospital with a 1 day history of headache, fever up to 39.9 °C, confusion, diarrhoea, and vomiting. He had a left-sided ptosis, reduced conscious level (Glasgow coma scale 8/15) and was hypertensive (blood pressure 134/90 mmHg). He required intubat...